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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
EUrost 2

ihad-Lipid Research and Innovation:

Cialis (tadalafil) is a lipase inhibitor. Lipases are gut enzymes that break down fat from food, enabling it to be absorbed and metabolized. By reducing blood flow, Cialis helps individuals manage lipids by increasing cholesterol and triglycerides.

Cialis isaring treatment for erectile dysfunction. The drug has a effect on lipoprotein and increases testosterone levels. It is indicated for men who have difficulty urinating or if treatment with this medicine is causing dizziness.

Cialis is also being explored for treatment of pulmonary arterial hypertension. The drug has been shown to improve exercise capacity and increase blood pressure in clinical trials.

Similar Pharmacy Names:

Cialis (tadalafil) is a prescription medication that is used to manage erectile dysfunction and is also used to treat pulmonary arterial hypertension.

Viagra Levitra 100mg Tablet contains sildenafil 50mg. It belongs to the class of medicines called phosphodiesterase type 5 (PDE5) inhibitors. It helps in the treatment and control of erectile dysfunction in men. Levitra 100mg Tablet will not cure the erectile dysfunction, which is an condition where the blood vessels are not functioning. Levitra 100mg Tablet will not treat any other condition.

Erectile dysfunction is a common condition affecting approximately 30 million men in Canada and over the counter. It is often linked to age, obesity, hypertension, cholesterol levels, and medications (prescription or over the counter) used to manage ED. Patient-reported outcomes (PROKles) that are associated with erectile dysfunction are improved sex life and reduced anxiety. While erectile dysfunction is common in men, it is not the fault of men themselves. It is the healthcare professionals who are the real culprit.

Viagra is a prescription medication that is used to treat erectile dysfunction in men. It works by relaxing the blood vessels in the penis, allowing for increased blood flow, and allowing the penis to become bigger and longer-lasting. Viagra Levitra 100mg Tablet is a phosphodiesterase type 5 inhibitor. It treats erectile dysfunction by improving blood flow to the penis.

Viagra Levitra 100mg Tablet should be taken in the dose and duration as advised by your doctor. The dosage and duration of Viagra Levitra 100mg Tablet will be determined by your doctor at your earliest convenience. It’s important to take Viagra Levitra 100mg Tablet as directed by your doctor, usually once daily.

Uses of Viagra Levitra 100mg Tablet

Erectile Dysfunction (ED) is the inability to achieve or maintain an erection sufficient for sexual intercourse. It can have a significant impact on a man’s self-esteem, relationships, and overall quality of life.

How does Viagra Levitra 100mg Tablet work?

Viagra Levitra 100mg Tablet works by relaxing the blood vessels in the penis, allowing for increased blood flow, and allowing the penis to become bigger and lasting.

How should I take Viagra Levitra 100mg Tablet?

Viagra Levitra 100mg Tablet is taken about 1 hour before sexual activity. It may take several attempts before successful treatment is achieved. Swallow the tablet whole with water.

How long does Viagra Levitra 100mg Tablet take to work?

The onset of Viagra’s action may vary from person to person, but it typically begins to work within 30 minutes to an hour. The effects can last for up to 4-6 hours.

Can I stop Viagra Levitra 100mg Tablet use after eating?

No, you should not stop Viagra Levitra 100mg Tablet after eating. However, you should continue to take Viagra Tablet after eating, as it can lessen the effectiveness of the medication and increase the likelihood of unwanted side effects.

Can I take Viagra Levitra 100mg Tablet every day?

No, Viagra Levitra 100mg Tablet is not recommended for use in children. It should be used only when required, as it may impair a nursing infant.

Can I take Viagra Levitra 100mg Tablet with alcohol?

While Viagra is effective, it may not work as effectively without alcohol. It’s best to avoid excessive alcohol consumption while taking Viagra.

How long does Viagra Levitra 100mg Tablet Last?

Viagra’s effects may wear off within a few hours. It is important to continue taking the medication for the duration it intended to provide.

Does Viagra 100mg Levitra 100mg Tablet cause tiredness?

Yes, Viagra Levitra 100mg Tablet can cause tiredness. You should exercise caution and consult a doctor if you experience fatigue after taking Viagra.

Does Viagra 100mg Levitra 100mg Tablet cause weakness?

Yes, Viagra Levitra 100mg Tablet may cause tiredness. You should use a lighted, light-coloured medicine like Cialis (tadalafil). You can also take it with a light meal.

Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questionnaire

What is Tadalafil?

Tadalafil is the generic version of the FDA-approved medication name brand, that is used to treat the health conditions listed below the prescription :

• Cialis (“tadalafil”) 50mg – is available as a generic medication as a single-dose, two-PRESS formulation (25mg and 100mg), and as an 8-week, 24-tablet formulation (20mg).

• Levitra (“vardenafil”) 2.5mg – is available as a single-dose, two-PRESS formulation (25mg and 100mg), and as an 8-week, 24-tablet formulation (20mg).

• Ajepng (“igenous-ts”) 2.5mg – is available as a single-dose, two-PRESS formulation (25mg and 100mg), and as an 8-week, 24-tablet formulation (20mg).

• Jardiance (“igenous-ts”) 2.5mg – is available as a single-dose, two-PRESS formulation (25mg and 100mg), and as an 8-week, 24-tablet formulation (20mg).

Tadalafil side effects

As with any medication, there is possible side effects with taking Tadalafil. The most common side effects are :

erennietal pain/ flushing

Back pain

Speak to your GP if you experience:

• Allergic to Tadalafil or any of its ingredients

• History of stroke or heart attack

• History of liver or kidney disease

• Tablet-induced vomiting

• Diarrhoea, constipation

• Palpitations

How long do Tadalafil should be taken for?

Tadalafil is usually taken for as long as your GP has recommended, and it will depend on which medications are taking you.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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